Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
US4601893A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 6, 1984 |
| Grant date | Jul 22, 1986 |
| Priority date | — |
| Expiry date | Dec 6, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Laminate device for the controlled and prolonged release of at least one active agent to an ambient environment comprising at least one core sheet, said core sheet or sheets comprising said agent or agents in a polymer matrix, and, in a preferred embodiment, a porosity enhancing agent in admixture with said agent; said core sheet or sheets being alternately sandwiched or interposed between coextensive inert polymeric films substantially impermeable to said environment and to said agent or agents, said device being perforated by one or a plurality of macroholes extending through said sheets and said films. In a modification of said device the perimeter edge thereof is coated by an inert polymeric film substantially impermeable to said environment and to said agent or agents. Also included are methods for making such a device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.