Mammalian metallothionein promoter system
US4601978A · kind A · utility
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16Claims
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Key dates
| Filing date | Nov 24, 1982 |
| Grant date | Jul 22, 1986 |
| Priority date | — |
| Expiry date | Nov 24, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A cloning vector comprises a replication system from a bovine papilloma virus, a regulatory system including the promoter and terminator from a human metallothionein II gene, and a prokaryotic replication system. The vector is useful for transforming mammalian cells where it is maintained as an automonously replicating episome. Transcription may be regulated by the presence of heavy metals and/or glucocorticoid hormones in the growth media.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.