Packing materials for chromatographic use and a method for analysis of an enantiomer mixture using the same
US4604207A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 18, 1984 |
| Grant date | Aug 5, 1986 |
| Priority date | — |
| Expiry date | Jan 18, 2004 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2220/58
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A packing material for chromatographic use which comprises an inorganic carrier having hydroxyl groups at the surface thereof having grafted thereon an .alpha.-arylalkylamine derivative which is formed by bonding an optically active .alpha.-arylalkylamine and an aminoalkylsilane through a dibasic carboxylic acid, and a method for liquid chromatographic analysis of an enantiomer mixture using this packing material as a stationary phase. The packing material of the present invention can be easily produced by the usual chemical reaction, is chemically stable, and exhibits excellent effects in the separation of an enantiomer mixture of a compound having an --NH-- group, --CONH-- group, or an --OCO-- group bonded to an asymmetric carbon atom thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.