1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives and pharmaceutical compositions containing them
US4605653A · kind A · utility
3Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 1985 |
| Grant date | Aug 12, 1986 |
| Priority date | — |
| Expiry date | Mar 19, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), ##STR1## wherein R.sup.1 and R.sup.2 are alkoxy having from 1 to 6 carbon atoms, PA1 X is oxygen or sulfur, PA1 Y is .dbd.O, .dbd.S or an .dbd.NR.sup.3 group, wherein PA2 R.sup.3 is hydrogen, alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms or optionally substituted phenyl, and acid addition and quaternary salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.