1-substituted pyrrolizidine derivatives and antiarrhythmic use thereof
US4605662A · kind A · utility
3Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 6, 1983 |
| Grant date | Aug 12, 1986 |
| Priority date | — |
| Expiry date | Sep 6, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel 1-substituted pyrrolizidine derivative having the formula: ##STR1## (wherein R.sup.1 is hydrogen or a lower alkyl group; R.sup.2 is hydrogen, a lower alkyl or lower alkoxy group, or a halogen; R.sup.3 is hydrogen, a lower alkyl, lower alkoxy or amino group, or a halogen), which can be produced by reacting 1-chlorocarbonyl (or alkoxycarbonyl)pyrrolizidine with a corresponding substituted aniline (or an alkali metal salt thereof). The pyrrolizidine derivative has antiarrhythmic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.