Patent · US Expired

Muramyldipeptide derivatives

US4606857A · kind A · utility

1Cited by
10References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 27, 1983
Grant dateAug 19, 1986
Priority date
Expiry dateJul 27, 2003

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/04
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Muramyldipeptide derivatives represented by the formula: ##STR1## wherein Ala represents alanine; Acyl represents an acyl group; R.sub.1 and R.sub.2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R.sub.3 represents a hydrogen atom, an acyl group or an alkyl group; and R.sub.4 represents a hydrogen atom or an alkyl group. These compounds have excellent immunoadjuvant activity, prophylactic and therapeutic effects against microbial infections, and antitumor activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.