Muramyldipeptide derivatives
US4606857A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 27, 1983 |
| Grant date | Aug 19, 1986 |
| Priority date | — |
| Expiry date | Jul 27, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Muramyldipeptide derivatives represented by the formula: ##STR1## wherein Ala represents alanine; Acyl represents an acyl group; R.sub.1 and R.sub.2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R.sub.3 represents a hydrogen atom, an acyl group or an alkyl group; and R.sub.4 represents a hydrogen atom or an alkyl group. These compounds have excellent immunoadjuvant activity, prophylactic and therapeutic effects against microbial infections, and antitumor activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.