Bone seeking Tc-99m complexes of phosphonate derivatives of polyamidoamines
US4606907A · kind A · utility
23Cited by
10References
19Claims
0Family size
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Key dates
| Filing date | Jul 2, 1984 |
| Grant date | Aug 19, 1986 |
| Priority date | — |
| Expiry date | Jul 2, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New stable complexing agents for radionuclides which are phosphonate derivatives of certain polyamidoamines have been found which are useful in imaging the skeletal system in animals. Even though the complexing agents have high molecular weights the complexes clear rapidly and very efficiently through the kidneys, with large amounts being taken up in the bone. The ratio of uptake in bone to that in surrounding soft tissue is high even at relatively short times after injection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.