Small particle formation and encapsulation
US4606940A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 21, 1984 |
| Grant date | Aug 19, 1986 |
| Priority date | — |
| Expiry date | Dec 21, 2004 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J13/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Process for the formation and the simultaneous encapsulation of small particles of a compound from solution which comprises: PA0 (a) dissolving said compound in a first solvent; PA0 (b) preparing a solution of encapsulating material and an electrolyte in a second solvent which is miscible with the first solvent and in which the compound to be encapsulated is more or less insoluble, in an amount which is effective, but present in an amount just insufficient to cause coacervation of the encapsulating material without interacting with it; PA0 (c) mixing the solutions from step (a) and (b) while stirring to cause the concurrent precipitation of the compound as small particles and formation of a coacervate of the encapsulating material; and PA0 (d) gelling the encapsulating material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.