Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist
US4607031A · kind A · utility
2Cited by
2References
15Claims
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Key dates
| Filing date | May 22, 1985 |
| Grant date | Aug 19, 1986 |
| Priority date | — |
| Expiry date | May 22, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65583
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An ethyl benzylphosphinate derivative represented by the general formula (I) ##STR1## wherein Y represents a hydrogen or fluorine atom, X represents a methylene group or an oxygen atom, and n is 2, 3 or 4. The said compounds can be produced by reacting a compound represented by the following formula (II) ##STR2## wherein Y is as defined above, with a compound represented by the following formula (III) ##STR3## wherein X and n are as defined, and M is an alkali metal atom, in an inert medium. These compounds are useful as a calcium antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.