Lipoxygenase inhibiting compounds
US4608390A · kind A · utility
43Cited by
4References
21Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 26, 1985 |
| Grant date | Aug 26, 1986 |
| Priority date | — |
| Expiry date | Apr 26, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## where X is selected from hydrogen, C.sub.1 to C.sub.22 alkyl or alkenyl, or an electron withdrawing group; PA1 n=0 or 1 and m=0, 1, 2 or 3; but n and m are not O simultaneously; PA1 R.sub.1 and R.sub.2 independently are hydrogen, C.sub.1 to C.sub.6 alkyl, an electron withdrawing group, or R.sub.4 ; PA1 R.sub.3 is H, C.sub.1 to C.sub.6 alkyl or cycloalkyl, or R.sub.4 ; and PA1 R.sub.4 independently at each occurrence, has the formula ##STR2## where Y is hydrogen or an electron withdrawing group; and wherein M is a pharmaceutically acceptable cation, are potent inhibitors of lipoxygenase enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.