5-(1-cyano-1-alkyl-N-methyl-N-methoxy-phenethyl)-alkylamino-2,2,8-trimeth yl-4H-dioxino-(4,5-c)-pyridine derivatives, and their use as calcium antagonistic agents
US4610990A · kind A · utility
4Cited by
0References
2Claims
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Assignee
Inventor
Key dates
| Filing date | Oct 3, 1985 |
| Grant date | Sep 9, 1986 |
| Priority date | — |
| Expiry date | Oct 3, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to new 5-(1-cyano-1-alkyl-N-methyl-N-methoxy-phenethyl)-alkylamino-2,2,8-trimethy l-4H-dioxino-(4,5-c)-pyridine derivatives of the formula ##STR1## and therapeutically acceptable salts of these compounds, to a preparation process of the same comprising reacting, in stoichiometric proportions, the corresponding 5-(1-cyano-1-R.sub.1)-methyl-2,2,8-trimethyl-4H-dioxino-(4,5-c)-pyridine of the formula ##STR2## on the appropriate [N-methyl-N-(methoxy-phenethyl)]-.omega.-alkyl chloride of the formula ##STR3## The invention relates also to therapeutic compositions containing said derivatives as active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.