Process for the preparation of .beta.-(benzothiazolylthio)- and .beta.-(benzimidazolylthio-carboxylic acids
US4612378A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 14, 1984 |
| Grant date | Sep 16, 1986 |
| Priority date | — |
| Expiry date | May 14, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The reaction of 2-mercapto-benzothiazole or -benzimidazole with .alpha.,.beta.-unsaturated carboxylic acids in a strongly acid reaction medium gives compounds of the formula I ##STR1## in which X is sulfur or NH, each radical R independently of one another is H, alkyl, halogenoalkyl, alkoxy, alkylthio, alkylsulfonyl, phenyl, alkylphenyl, phenylalkyl, cycloalkyl, halogen, NO.sub.2, CN, COOH, COOalkyl, OH or an amino or carbamyl group and R.sup.1, R.sup.2 and R.sup.3 independently of one another are H, alkyl, halogenoalkyl, hydroxyalkyl, alkoxyalkyl, carboxyalkyl, carboxyl or unsubstituted or substituted aryl or aralkyl, or R.sup.1 and R.sup.2 together are straight-chain or branched alkylene, which can be substituted by 1 or 2 carboxyl groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.