Method and system for externally treating the blood
US4613322A · kind A · utility
Inventor
Key dates
| Filing date | Mar 29, 1983 |
| Grant date | Sep 23, 1986 |
| Priority date | — |
| Expiry date | Mar 29, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S128/03
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and system are disclosed for externally treating human blood, with the objective of reducing the functioning lymphocyte population in the blood system of a human subject. According to the method, blood is withdrawn from the subject and passed through an ultraviolet radiation field in the presence of a dissolved photoactive agent capable of forming photo-adducts with lymphocytic-DNA, mobile hormonal hormonal receptors or antigen sites to thereby effect covalent bonding between the photoactive agent and the same, thereby inhibiting the metabolic processes of the lymphocytes or complexing them; and thereupon returning the irradiated blood to the subject. The withdrawn blood may be formed into an extracorporeal stream and flowed through a treatment station whereat the irradiation is effected, as for example by exposure to UV radiation; and such flow process may be conducted on a continuous basis. If desired, the blood to be treated may be separated to provide a blood fraction rich in lymphocytes and low in any blood component which absorbs UV radiation, as for example by continuous centrifuging which fraction is then irradiated with UV radiation in the presence of a dissolved …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.