Patent · US Expired

Method for treating disorders of lipid metabolism using benzene sulfonamides

US4613618A · kind A · utility

7Cited by
1References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 16, 1982
Grant dateSep 23, 1986
Priority date
Expiry dateJun 16, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/34
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to new medicaments having lipid regulating properties and processes for their preparation. The medicaments according to the invention contain as active principle at least one compound, (or its corresponding optical isomer) of the arylsulfonamide type corresponding to the formula: ##STR1## in which: Ar represents an aromatic ring which may if necessary be substituted; PA0 n+m+1 is comprised from 3 to 11, being preferably equal to 3,5 or 10, or is comprised from 1 to 11 when Ar represents an aryl group in which at least one of the R.sub.1,R.sub.2 and R.sub.3 radicals is a CF.sub.3 group; PA0 R.sub.5 and R.sub.6 represent independently of one another particularly an alkyl radical; PA0 R.sub.4 represents the hydroxy group, the radical OR.sub.7 in which R.sub.7 is particularly an alkyl group, the radical NR.sub.8 R.sub.9 in which R.sub.8 and R.sub.9 are identical or different, and represent in particular a hydrogen atom, and form with the nitrogen a nitrogenous heterocyclic ring with 5 or 6 links.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.