N-nitroso compounds and compositions containing such compounds
US4613695A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 6, 1983 |
| Grant date | Sep 23, 1986 |
| Priority date | — |
| Expiry date | Sep 6, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/47
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns N-nitroso compounds having the general formula: ##STR1## wherein A is lower alkyl or halolower alkyl; PA0 B is hydrogen; lower alkenyl; lower alkynyl; 3-6 C cycloalkyl; --RSO.sub.2 NR.sup.3 R.sup.4, or lower alkyl optionally monosubstituted with lower alkoxy, or 3-6 C cycloalkyl; PA0 R is straight or branched 2-5 C alkylene, optionally monosubstituted with SO.sub.2 NR.sup.3 R.sup.4 or CONR.sup.3 R.sup.4, said alkylene always containing at least two carbon atoms separating the nitrogen atom of the urea from any SO.sub.2 NR.sup.1 R.sup.2 or SO.sub.2 NR.sup.3 R.sup.4 ; PA0 R.sup.1 and R.sup.2 are the same or different and selected from hydrogen, 5-6 C cycloalkyl, lower alkoxy, phenyl, benzyl, and straight or branched 1-6 C alkyl, optionally monosubstituted with hydroxy, lower alkoxy, SO.sub.2 NR.sup.3 R.sup.4, or CONR.sup.3 R.sup.4 ; R.sup.1 and R.sup.2 may also together form a 4-5 C alkylene; and R.sup.3 and R.sup.4 are the same or different and selected from hydrogen or lower alkyl, or R.sup.3 and R.sup.4 together are a 4-5 C alkylene, together with pharmaceutical compositions thereof; processes for their manufacture, and methods of treatment. The compounds of…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.