Drug dispensing wound dressing
US4614787A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1984 |
| Grant date | Sep 30, 1986 |
| Priority date | — |
| Expiry date | Nov 13, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/418
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The disclosed wound dressings have a drug dispersed throughout a polyurethane matrix that is the reaction product of: (A) An isocyante terminated prepolymer formed by reaction of isophorone diisocyanate and a macroglycol and (B) a monomer containing hydroxyl and vinyl groups. The reaction product is a vinyl terminated polyurethane oligomer which is liquid at room temperature and which may be readily admixed with a pharmacoactive substance and a photosensitizer, formed into a film and cured by exposure to UV light without release of heat. In the most preferred embodiments the foregoing oligomer is codissolved in an organic solvent with a polyurethane polymer which is the reaction product of: PA0 dicyclohexyl methane diisocyanate; PA0 a polytetramethylene ether polyol having a molecular weight in the range of 1000-3000 daltons; and PA0 1,4-butane diol. That solution is then admixed with the pharmacoactive agent, formed into a film and cured.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.