Patent · US Expired

Purification of biologically active human immune interferon

US4617378A · kind A · utility

6Cited by

3References

14Claims

0Family size

Assignee

YEDA RESEARCH AND DEVELOPMENT CO. LTD. · IL

Inventors

Menachem Rubinstein · Nes Ziona, IL
Jossef Friedlander · Bat Yam, IL
Dina Fischer · Ramat Gan, IL

Key dates

Filing date	Jan 18, 1984
Grant date	Oct 14, 1986
Priority date	—
Expiry date	Jan 18, 2004

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01D2313/40
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

There is provided a process for purification of human immune interferon (IFN-.gamma.) to homogeneity without appreciable loss of biological activity by the use of chromatography on controlled-pore glass, ultrafiltration and high performance cation exchange chromatography, resulting in essentially pure human interferon subtypes 21K and 26K, and there are provided said purified interferons and pharmaceutical compositions containing same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.