Mitomycin analogs
US4617389A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 15, 1983 |
| Grant date | Oct 14, 1986 |
| Priority date | — |
| Expiry date | Dec 15, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antineoplastic compounds of the formula, IIa, ##STR1## wherein: Y is hydrogen or lower alkyl; and Z is a lower alkoxy substituted quinolinylamino radical, a cyano substituted pyrazolylamino radical or a mono- or di-lower alkyl substituted thiazolamino radical, or PA0 a nitrogen-containing heterocyclic radical, or PA0 a cyano, phenyl, carboxamido or lower alkoxycarbonyl substituted 1-aziridinyl radical or PA0 a lower alkyl, formyl or acetylphenyl substituted 1-piperazinyl radical, or PA0 an hydroxy or piperidyl substituted 1-piperidyl radical, or PA0 a lower alkoxy, amino or halo substituted pyridylamino radical, or PA0 a carboxamido, mercapto or methylenedioxy substituted anilino radical, or PA0 a radical of the formula, ##STR2## wherein R is hydrogen or lower alkyl and R" is a nitrogen-containing heterocyclic radical, or PA0 a butyrolactonyl radical, or PA0 an adamantyl radical, or PA0 a mono- lower alkoxy substituted phenyl radical, or PA0 a substituted lower alkyl radical selected from the group consisting of mercapto lower alkyl, carboxy lower alkyl, mono-, di- and tri-lower alkoxy lower alkyl, lower alkyl thio lower alkyl and lower alkoxycarbonyl substituted derivatives thereo…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.