Ethynylation of 16-methyl-17-keto steroids
US4618456A · kind A · utility
1Cited by
11References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 26, 1984 |
| Grant date | Oct 21, 1986 |
| Priority date | — |
| Expiry date | Apr 26, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0015
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The process of the present invention transforms 16.alpha.- or 16.beta.-methyl-17-keto steroids (I) to the corresponding 17.alpha.-ethynyl-17.beta.-hydroxy-16.alpha.- or 16.beta.-methyl steroids (II) without epimerization and loss of stereochemistry of the 16.alpha.- or 16.beta.-methyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.