1-(aminoalkoxyphenyl)-1-phenyl-propanols, process for their preparation and pharmaceutical compositions containing them
US4618611A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1983 |
| Grant date | Oct 21, 1986 |
| Priority date | — |
| Expiry date | Dec 27, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new aminopropanol derivatives of the formula (I) ##STR1## wherein R.sub.1 is halogen, trihalomethyl, alkoxy having from one to 3 carbon atoms or alkyl having from one to 3 carbon atoms, PA0 R.sub.2 is alkyl having from one to 3 carbon atoms, and PA0 R.sub.3 is cycloalkyl having from 3 to 6 carbon atoms, or PA0 R.sub.2 and R.sub.3 together with the nitrogen they are attached to form an up to 8 membered ring optionally containing oxygen or a further nitrogen as an additional hetero atom, and optionally substituted with alkyl having from one to 4 carbon atoms or benzyl, and acid addition and quaternary ammonium salts thereof. According to another aspect of the invention there are provided processes for the preparation of these compounds. The new compounds are suitable for the treatment of acute ethanolic intoxication. Pharmaceutical compositions containing them are also within the scope of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.