Sulfonates of hydroxycoumarins

US4618622A · kind A · utility

Assignee

• BASF SE

Inventors

• Rainer Schlecker · Bissersheim, DE
• Peter Schmidt · Chanhassen, US
• Peter C. Thieme · Monsheim, DE
• Dieter Lenke · Ludwigshafen, DE
• Hans-Jurgen Teschendorf · Dudenhofen, DE
• Martin Traut · Heidelberg, DE
• Claus Mueller · Allschwil, CH
• Hans P. Hofmann · Schifferstadt, DE
• Horst Kreiskott · Monsheim, DE

Key dates

• Filing date: Nov 17, 1983
• Grant date: Oct 21, 1986
• Expiry date: Nov 17, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D311/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Sulfonates of hydroxycoumarins of the formula I ##STR1## where R.sup.1 and R.sup.2 are identical or different and are each hydrogen, halogen or alkyl of 1 to 5 carbon atoms which can be substituted by --NR.sup.4 R.sup.5, --OR.sup.4 or --OC(O)R.sup.4, where R.sup.4 and R.sup.5 are identical or different and are each hydrogen or alkyl of 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 are each a carboxylic acid group --OC(O)R.sup.4 or a carboxamido radical, with the proviso that R.sup.1 is not methyl when R.sup.2 is hydrogen, or R.sup.1 and R.sup.2 together form a --(CH.sub.2).sub.n -- chain where n is 3-5, and R.sup.3 is a straight-chain or branched alkyl radical of 1 to 8 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, each of which can be substituted by halogen, --OR.sup.4, --NR.sup.4 R.sup.5, --CN or phenyl, or R.sup.3 is a straight-chain or branched alkenyl radical of 3 to 8 carbon atoms, an amino group -- NR.sup.4 R.sup.5, or phenyl or naphthyl, each of which is unsubstituted or monosubstituted or polysubstituted by --OR.sup.4, --NR.sup.4 R.sup.5, --NO.sub.2, halogen, --SR.sup.4, --S(O)R.sup.4, --OS(O)R.sup.4, --SCF.sub.3, --OS(O)CF.sub.3, --CN, --C(O)R.sup.4, --OC(O)R.sup.4, --…