Patent · US Expired

Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors

US4619938A · kind A · utility

11Cited by

2References

7Claims

0Family size

Assignee

Terumo Kabushiki Kaisha · JP

Inventors

Keiko Takahashi · Tokyo, JP
Yasushi Suwabe · Tokyo, JP
Toshio Wakabayashi · Mito, JP

Key dates

Filing date	Mar 19, 1985
Grant date	Oct 28, 1986
Priority date	—
Expiry date	Mar 19, 2005

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D213/81
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Alkanolamine derivatives and platelet aggregation inhibitors containing the same as an active ingredient are disclosed. The alkanolamine derivatives are novel compounds which possess potent platelet aggregation inhibitory activities and effective in preventing diseases such as thrombosis. As typical compounds are mentioned N-5,8,11,14,17-eicosapentaenoyl-2-aminoethanol, N-nicotinoyl-2-aminoethyl-5,8,11,14,17-eicosapentaenoate, N-ethyl-N-5,8,11,14,17-eicosapentaenoyl-2-aminoethanol, N-butyl-N-5,8,11,14,17-eicosapentaenoyl-2-aminoethanol, N-5,8,11,14,17-3-aminopropylnicotinate, (N-ethyl-N-nicotinoyl-2-aminoethyl)-5,8,11,14,17-eicosapentaenoate and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.