Patent · US Expired

Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

US4623650A · kind A · utility

31Cited by

4References

17Claims

0Family size

Assignee

PFIZER INC. · US

Inventors

Paul J. Gilligan · Wilmington, US
Paul Robert McGuirk · Gales Ferry, US
Michael John Witty · Dover, GB

Key dates

Filing date	Dec 6, 1984
Grant date	Nov 18, 1986
Priority date	—
Expiry date	Dec 6, 2004

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F7/1804
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

1-Substituted-6-fluoro-7-aryl-(8-fluoro)-1,4-dihydroquinol-4-one 3-carboxylic acids having antibacterial activity are prepared by reacting the corresponding alkyl 1-substituted-6-fluoro-7-bromo-(8-fluoro)-1,4-dihydroquinol-4-one-3-carbox ylate with an arylmetallic compound and hydrolyzing the ester formed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.