Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
US4624846A · kind A · utility
108Cited by
9References
17Claims
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Key dates
| Filing date | Jul 24, 1984 |
| Grant date | Nov 25, 1986 |
| Priority date | — |
| Expiry date | Jul 24, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/866
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for enhancing target specificity of antibody localization comprises injecting a second antibody specific to a labeled target-specific antibody to reduce the level of non-targeted circulating specific antibody, thereby increasing the localization ratio. The foregoing method is useful for imaging tumors and infectious lesions, and for therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.