Cell-delivery agent
US4625014A · kind A · utility
103Cited by
3References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1984 |
| Grant date | Nov 25, 1986 |
| Priority date | — |
| Expiry date | Jul 10, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A photo-cleavable compound for delivery and release of a biologically active substance to selected target cells; the compound includes a binding partner for a specific cell-surface receptor of those target cells, the biologically active substance to be delivered, and a photo-cleavable bridge between the binding partner and the biologically active substance. When the compound is exposed to a heterogeneous population of target and non-target cells, it binds selectively to the receptors on the surface of the target cells. Exposing the compound to light of selected wave length cleaves it, yielding the active substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.