Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts

US4625024A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Erwin Schmidt · Baltmannsweiler, DE
• Karl Clauss · Hofheim, DE

Key dates

• Filing date: Aug 5, 1985
• Grant date: Nov 25, 1986
• Expiry date: Aug 5, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D291/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts are prepared by reacting acetoacetamide with an S-O compound of the formula I EQU FSO.sub.2 Y (I) wherein Y.dbd.F, Cl, --OSO.sub.2 F or --OSO.sub.2 Cl, preferably only F, in the presence of bases. The non-toxic salts--especially the potassium salt--are valuable synthetic sweeteners.