Erodible matrix for sustained release bioactive composition
US4629621A · kind A · utility
107Cited by
3References
83Claims
0Family size
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Inventor
Key dates
| Filing date | Jul 23, 1984 |
| Grant date | Dec 16, 1986 |
| Priority date | — |
| Expiry date | Jul 23, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/298
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of PA0 5 to 95% by weight of a polyethylene glycol having a molecular weight of from about 1000 to about 20,000, and PA0 95 to 5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.