Patent · US Expired

Useful in radiotherapy of chemotherapy 4-aziridino-1-nitroimidazol-1-yl-2,3-butanediols

US4631289A · kind A · utility

10Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 27, 1983
Grant dateDec 23, 1986
Priority date
Expiry dateMay 27, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound of formula I ##STR1## in which formula: R.sub.1 represents hydrogen or an alkyl group; PA0 R.sub.2 -R.sub.5 represent hydrogen, alkyl aryl, aralkyl or alkaryl group; and PA0 n is 2. The compounds are used as a radiation sensitizing agent or a chemopotentiating agent for administration to a patient undergoing radiation therapy or chemotherapy for the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.