Patent · US Expired

Novel radioactive estratrienes

US4632820A · kind A · utility

0Cited by
2References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 1983
Grant dateDec 30, 1986
Priority date
Expiry dateDec 12, 2003

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/534
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Novel radioactive .DELTA..sup.4,9,11 -estratrienes marked with iodine 125 or 131 having the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 2 to 12 carbon atoms, R.sub.1 is the reminder of an amino acid of the formula R.sub.1 NH.sub.2 or a derivative thereof being marked with iodine 125 or 131 and the wavy lines indicate the --OR is in the .alpha.- or .beta.-position and the oximido group is in the syn or anti position, a process and intermediates for their preparation, antigens prepared therefrom and use thereof to prepare antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.