Conjugates of anticoagulant and protein
US4634762A · kind A · utility
20Cited by
8References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1985 |
| Grant date | Jan 6, 1987 |
| Priority date | — |
| Expiry date | Mar 26, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08H1/00
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Conjugates are provided which are covalently bonded conjugates of an anticoagulant and protein that are prepared in the presence of a coupling agent that forms amide linkages between the anticoagulant and the protein. Such amide linking coupling agents exclude highly toxic coupling agents such as CNBr. These conjugates are useful for enhancing the blood compatibility of certain surfaces of a prosthetic device, a surgical apparatus, or an extra-corporeal medical device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.