Monoclonal anti-ornithine decarboxylase antibody and method of producing same
US4637984A · kind A · utility
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Key dates
| Filing date | Oct 11, 1983 |
| Grant date | Jan 20, 1987 |
| Priority date | — |
| Expiry date | Oct 11, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/864
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Monoclonal anti-ornithine decarboxylase antibody is produced by cell hybrids between hypoxanithine phosphoriboxyltransferase deficient myeloma cells and spleen cells derived from an animal previously immunized with ornithine decarboxylase. By means of immunoaffinity chromatography using cyanogen bromide-activated agarose coupled with the antibody, ornithine decarboxylase in animal cell extracts can be highly purified in high yield.
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