Drug release system
US4638043A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1985 |
| Grant date | Jan 20, 1987 |
| Priority date | — |
| Expiry date | Aug 23, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/608
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A drug releasing system in the form of a medical patch comprised of a drug dispensing polyurethane member as a matrix for a therapeutically effective amount of drug dispersed therein. The polyurethane of the drug dispensing or releasing member is a polyurethane acrylic copolymer which is the reaction product of an oligomer of a diisocyanate, a glycol with a molecular weight between the range of 500-5,000 molecular weight units and an acrylyl chain terminator having a molecular weight between the range of 40-200 molecular weight units cured by actinic radiation. In its preferred embodiment, the foregoing drug releasing or dispensing member is incorporated into a medical patch or drug release system comprised of successive layers of an ultrathin polyurethane substrate, pressure sensitive adhesive, the above-described drug releasing member and optionally a second layer of adhesive. The drug release system of the present invention is biocompatible, oxygen and water vapor permeable, flexible and can incorporate a wide variety of drugs for a controlled, sustained release to the wearer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.