Patent · US Expired

Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate

US4639338A · kind A · utility

20Cited by

8References

11Claims

0Family size

Assignees

Ciba-Geigy · US
Henkel Kommanditgesellschaft auf Aktien · DE

Inventors

Peter H. Stahl · Glückstadt, DE
Beat Schmitz · Allschwil, CH

Key dates

Filing date	Jul 29, 1985
Grant date	Jan 27, 1987
Priority date	—
Expiry date	Jul 29, 2005

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a novel crystal modification, containing water of crystallization, of disodium 3-amino-1-hydroxypropane-1,1-diphosphonate of the formula ##STR1## and to a process for the manufacture thereof. This modification is suitable for the oral treatment of disorders of the calcium and phosphate metabolism and associated diseases in warm-blooded animals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.