Arylic derivatives of piperazine, the method of preparing same and their application in therapeutics
US4639452A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 25, 1983 |
| Grant date | Jan 27, 1987 |
| Priority date | — |
| Expiry date | Feb 25, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D319/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New derivatives are provided corresponding to the formula: ##STR1## in which Ar represents an aromatic nucleus; and X represents: either the trans ##STR2## chain or the ##STR3## chain and A=CONHOH, COOEt, COOH or CONR.sub.2 R.sub.3, either the trans-CH.dbd.CH--CH.sub.2 -- chain or --CH.sub.2 --CH.sub.2 --CH.sub.2 chain and A=carboxamido, N-isopropylcarboxamido, pyrrolidinocarbonyl or piperidinocarbonyl. These derivatives and their salts are used as drug for their activity stimulating, protecting and/or correcting cerebral functions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.