Patent · US Expired

Arylic derivatives of piperazine, the method of preparing same and their application in therapeutics

US4639452A · kind A · utility

9Cited by
5References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 25, 1983
Grant dateJan 27, 1987
Priority date
Expiry dateFeb 25, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D319/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

New derivatives are provided corresponding to the formula: ##STR1## in which Ar represents an aromatic nucleus; and X represents: either the trans ##STR2## chain or the ##STR3## chain and A=CONHOH, COOEt, COOH or CONR.sub.2 R.sub.3, either the trans-CH.dbd.CH--CH.sub.2 -- chain or --CH.sub.2 --CH.sub.2 --CH.sub.2 chain and A=carboxamido, N-isopropylcarboxamido, pyrrolidinocarbonyl or piperidinocarbonyl. These derivatives and their salts are used as drug for their activity stimulating, protecting and/or correcting cerebral functions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.