Patent · US Expired

3-substituted carbacepem compounds having antibacterial effect

US4640919A · kind A · utility

3Cited by
4References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 19, 1985
Grant dateFeb 3, 1987
Priority date
Expiry dateFeb 19, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D463/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Carbacephem compounds represented by the formula: ##STR1## [wherein R.sub.1 is a lower alkylsulfonyloxy, unsubstituted or substituted arylsulfonyloxy, azido, cyano, carbamoyloxy, unsubstituted or substituted heterocyclic thio ("heterocyclic" means a 5- or 6-membered heterocyclic group having 1 to 4 O, S or N atoms), unsubstituted or substituted lower alkylthio, or unsubstituted or substituted arylthio group; R.sub.2 and R.sub.3 are groups frequently used in the cephalosporin chemistry] have strong antibacterial activity against Gram-positive and Gram-negative bacteria, and are useful for curing various infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.