Substituted heterocyclyl-phenyl-(sulfonyl-or phosphonyl)-amidines
US4643993A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 18, 1983 |
| Grant date | Feb 17, 1987 |
| Priority date | — |
| Expiry date | May 18, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6518
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein Het is a heterocycle containing 2 to 3 nitrogen atoms; PA1 R is hydrogen, lower alkyl, alkoxy of 1 to 3 carbon atoms or halogen; PA1 Y is --SO.sub.3 H or ##STR2## R" is alkyl of 1 to 3 carbon atoms; and R' is straight or branched alkyl which may contain a heteroatom such as sulfur, oxygen or nitrogen; straight or branched alkenyl; cycloalkyl; alkyl-cycloalkyl; aryl; or aralkyl optionally substituted by lower alkyl, alkoxy of 1 to 3 carbon atoms or halogen; tautomers thereof, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as anti-ulcerogenics and gastric acid secretion inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.