Novel organic trithio oxides and method for the preparation thereof
US4643994A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 17, 1984 |
| Grant date | Feb 17, 1987 |
| Priority date | — |
| Expiry date | Dec 17, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C381/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel organic trithio oxides of the formula: EQU R.sup.1 --X --R--X.sup.1 --R.sup.1 wherein R is selected from --CH.sub.2 CH.dbd.CH--, ##STR1## and (CH.sub.2).sub.3 ; X is selected from ##STR2## X.sup.1 is selected from --S--S, ##STR3## and, each R.sup.1 is independently selected from carboxyalkyl, alkoxy, alkylthio, amino, alkylamino and acyl substituted and unsubstituted lower alkyl, lower alkenyl, lower alkynyl, phenyl and lower alkylphenyl; provided when R is --CH.sub.2 CH.dbd.CH--, X is ##STR4## and X.sup.1 is --S--S--, then R.sup.1 is not in both instances --CH.sub.2 CH.dbd.CH.sub.2. This invention also relates to a method of preparing the above-identified compounds by heating and further oxidizing various oxides of organic disulfides and to antithrombotic uses of the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.