Method for preparing specific inhibitors of virus-specified proteases
US4644055A · kind A · utility
48Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 17, 1984 |
| Grant date | Feb 17, 1987 |
| Priority date | — |
| Expiry date | Dec 17, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/223
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A general method for preparing specific inhibitors of virus-specified proteases is disclosed. The inhibitors comprise a halomethyl ketone or methyl ketone moiety covalently linked to a peptide sequence of three, four or five amino acids or amino acid residues, which peptide sequence corresponds to an amino acid sequence found adjacent to and upstream of a cleavage site recognized by a virus-specified protease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.