Increasing labeling efficiency by forming diagnostic agent in the presence of ascorbic acid or the like
US4645660A · kind A · utility
15Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1984 |
| Grant date | Feb 24, 1987 |
| Priority date | — |
| Expiry date | Apr 26, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A radioactive diagnostic agent having high labeling efficiency, prepared by bringing an aqueous solution of a radioactive metallic element contaminated with a non-radioactive metallic ions into contact with a non-radioactive carrier comprising a carrier substance having a chelate-forming property and optionally a physiologically active substance chemically bonded thereto, at least one of said aqueous solution and said non-radioactive carrier comprising at least one reductive material chosen from ascorbic acid and erythrobic acid, and their salts and esters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.