Tetracyclo compounds and a pharmaceutical composition containing the same
US4645765A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 11, 1985 |
| Grant date | Feb 24, 1987 |
| Priority date | — |
| Expiry date | Jun 11, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
New tetracyclo compounds of the formula: ##STR1## in which R.sup.1 is formyl, protected formyl, hydroxymethyl, protected hydroxymethyl, arylaminomethyl, carboxy, protected carboxy or substituted iminomethyl, PA1 R.sup.2 is hydroxy, alkoxy or protected hydroxy, PA1 R.sup.3 is hydrogen and R.sup.4 is methyl, hydroxymethyl or protected hydroxymethyl, or PA1 R.sup.3 and R.sup.4 are combined together to form methylene or oxo, PA1 R.sup.5 is hydroxy, alkoxy or protected hydroxy, and PA1 R.sup.6 is hydrogen, imino-protective group or alkyl, and pharmaceutically acceptable salts thereof, which have pharmacological activities such as antitumor activity, antimicrobial activity, and the like, and a process for their production and a pharmaceutical composition containing the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.