Generalized cytometry instrument and methods of use
US4647531A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Feb 6, 1984 |
| Grant date | Mar 3, 1987 |
| Priority date | — |
| Expiry date | Feb 6, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/813
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A generalized cytometry instrument for measuring the kinetic properties of live cells. Cells are immobilized on a surface and their positions determined and stored in memory by a central control computer. The cells are subsequently illuminated and an optical interaction detected. By taking many measurements of many cells, each of whose position and respective data is stored permitting subsequent reexamination and determination of activity as a function of time, respectively; the kinetic properties of large populations of cells may be studied in the presence of a variety of stimulating environments. Such stimulations may arise from contact with various reagents, including antigens, mitogens and peptides as well as electrical and mechanical perturbations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.