Patent · US Expired

Method for determination of hydrogen peroxide by chemiluminescence analysis

US4647532A · kind A · utility

22Cited by
11References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 22, 1985
Grant dateMar 3, 1987
Priority date
Expiry dateMar 22, 2005

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/206664
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for determination of hydrogen peroxide by chemiluminescence analysis which consists of reacting a sample containing hydrogen peroxide with an oxidizable non-fluorescent substance in the presence of an oxidizing catalyst to convert the non-fluorescent substance to a fluorescent substance, reacting the fluorescent substance with an oxalic acid di-ester and hydrogen peroxide in the presence of an inhibitor which inactivates the oxidizing catalyst, and then measuring the amount of light emission produced to determine the amount of hydrogen peroxide contained in the sample. Determination and enzyme immunoassay for a component other than hydrogen peroxide in a sample from living body and evaluation of bactericidal activity in phagocytosis of leukocytes by utilizing this method are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.