Process for the isolation of 2,2-dimethyl-7-hydroxy-coumaran

US4647676A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Manfred Lenthe · Odenthal, DE
• Udo Allenbach · Cologne, DE
• Gerhard Buttner
• Karl-Friedrich Christmann · Dormagen, DE

Key dates

• Filing date: May 23, 1984
• Grant date: Mar 3, 1987
• Expiry date: May 23, 2004

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C41/38
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the isolation of a dihydroxybenzenemonoether from a reaction mixture containing solvent, ether and unreacted dihydroxybenzene, comprising contacting the reaction mixture with at least one hydrocarbon which is not miscible or only partially miscible with the reaction mixture, the ether selectively entering the hydrocarbon. Advantageously the reaction for the preparation of the monoether is carried out in an alcohol, a ketone, a dipolar aprotic solvent or a polyhydroxyalkyl ether, or a mixture thereof with water, the hydrocarbon used as extracting agent has a boiling point between about 80.degree. and 300.degree. C., and the extraction is carried out in the presence of water whereby there is an increase in the selectivity of the extraction.