1,2,4-triazines
US4649139A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 22, 1984 |
| Grant date | Mar 10, 1987 |
| Priority date | — |
| Expiry date | Oct 22, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of Formula I are novel and useful as cardiovascular agents, particularly anti-arrhythmic agents: ##STR1## or the 5-imino-tautomer thereof or a salt of either, wherein R.sup.1 is C.sub.1-10 alkyl, C.sub.2-10 alkenyl, C.sub.2-10 alkynyl or C.sub.3-10 cycloalkyl, any of which is optionally substituted, and R.sup.2 to R.sup.6 are independently selected from hydrogen, halogen atom, C.sub.1-6 alkyl, alkenyl or alkynyl (all optionally substituted by one or more of halogen, hydroxy and aryl, amino, mono- or di-substituted amino, alkoxy (optionally substituted by one or more of halogen, hydroxy and aryl), alkenyloxy, aryl, acyloxy, cyano, nitro, aryl and alkylthio groups or any adjacent two of R.sup.2 to R.sup.6 are linked to form a (--CH.dbd.CH--CH.dbd.CH--) group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.