Patent · US Expired

Continuous lymphocyte cell lines, their production and use

US4652522A · kind A · utility

12Cited by
11References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 5, 1983
Grant dateMar 24, 1987
Priority date
Expiry dateJul 5, 2003

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/948
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method for producing continuous B lymphocyte cell lines and monoclonal antibodies by such lines is provided. DNA isolated from neoplastic cells is introduced into stimulated lymphocytes. Individual cells that have been transformed by the added DNA and that produce antibodies are clonally expanded. Cultures of these continuous cells are employed to produce monoclonal antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.