Retinoic acid derivatives, process for their preparation and pharmaceutical and cosmetic compositions containing them
US4654354A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 23, 1985 |
| Grant date | Mar 31, 1987 |
| Priority date | — |
| Expiry date | Sep 23, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q19/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of formula ##STR1## in which formula R.sub.1 and R.sub.2 are identical or different and denote: PA0 (1) taken separately: a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, an unsubstituted phenyl radical or a phenyl radical substituted with a halogen atom, with a C.sub.1 -C.sub.4 alkoxy radical or with a C.sub.1 -C.sub.4 alkoxy radical; PA0 (2) taken together either PA1 (a) a polymethylene linkage; or PA1 (b) a benzene ring; or PA1 (c) a cyclic linkage containing a nitrogen atom to constitute an isothiazolopyridinone derivative; m being able to have the values 0 or 1; PA0 the group A in the formula (IV) denoting the group ##STR2## where R.sub.8 corresponds to a hydrogen atom, a methyl radical, a hydroxymethyl radical or a --CH.sub.2 O--CO--Ret group. The invention also provides a process for preparing the abovementioned compounds and also drug compositions and cosmetic compositions containing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.