Galenical administration form of METOCLOPRAMIDE, method for its preparation and medicament comprising the new form
US4656024A · kind A · utility
Inventor
Key dates
| Filing date | May 3, 1984 |
| Grant date | Apr 7, 1987 |
| Priority date | — |
| Expiry date | May 3, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/166
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new galenic form with delayed release of METROCLOPRAMIDE, useful for gastric treatment, is formed by microgranules comprising a neutral core formed by a grain of an inert excipient comprising at least two components of the type belonging to the class formed by saccharose, starch, talc, desiccating silica, lactose and stearic acid, this neutral grain being provided with a first layer comprising METOCLOPRAMIDE, then a second outer layer formed by a microporous envelope comprising at least one natural and/or synthetic polymer belonging to the class formed by shellac, gum arabic, ethyl cellulose, cellulose acetophtalate, cellulose triacetate, polyoxyethyleneglycol, the methacrylates, styrene-acrylonitrile copolymer and polyvinylpyrrolidone in successive envelopes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.