Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
US4656132A · kind A · utility
20Cited by
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10Claims
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Key dates
| Filing date | Mar 28, 1984 |
| Grant date | Apr 7, 1987 |
| Priority date | — |
| Expiry date | Mar 28, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for improving the yield of heterologous protein such as IFN-.alpha., IFN-.beta., and IL-2, produced by recombinant bacteria by supplementing the nutrient medium in which the bacteria are grown with a water soluble alcohol and/or amino acid mixture during the terminal phase of the cultivation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.