Patent · US Expired

Isoquinoline derivatives, and pharmaceutical compositions containing them

US4656179A · kind A · utility

3Cited by
0References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 25, 1984
Grant dateApr 7, 1987
Priority date
Expiry dateOct 25, 2004

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB82Y10/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to new 1-[bis(hydroxymethyl)-methyl]-3,4-dihydro- or -1,2,3,4-tetrahydroisoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms, PA1 R.sup.3 is hydrogen or a single electron pair, PA1 and the dotted line represents an optional double bond, and salts thereof. The new compounds are useful intermediates in the preparation of other, pharmaceutically active isoquinoline derivatives or are pharmaceutically active themselves.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.