Operator-interactive automated chromosome analysis system producing a karyotype
US4656594A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 6, 1985 |
| Grant date | Apr 7, 1987 |
| Priority date | — |
| Expiry date | May 6, 2005 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V20/69
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
An operator-interactive automated chromosome analysis system is employed by an operator to locate and identify acceptable metaphase spreads, form a karyotype by rearranging the identified metaphase spreads in accordance with a predetermined arrangement of the twenty-three pairs of chromosomes naturally occurring in human beings, and display the karyotype on a display or a hardcopy printout, or both. The system comprises the following elements: a mechanized microscope system; a microscope and closed circuit television arrangement for microscopically scanning the chromosome spreads; a metaphase detector producing an output indicating metaphase detection; a television monitor for viewing the detected metaphase spreads; a photographic printer for producing a hardcopy representation of the detected metaphase spreads; and a computer, including a video interface, for controlling the mechanized microscope stage to locate the metaphase spreads, for analyzing the metaphase detector output to determine the location and grades of metaphases, for displaying a patient identifier on the monitor or hardcopy, and for rearranging and displaying the detected metaphase spreads so as to produce the kar…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.